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J Pathol 2007, 170:1763–1780.PubMedCrossRef Competing interests The authors declare that they have no competing interests. Authors’ contributions W Sun and YZ Fan were responsible for data collection and analysis, experiment job, interpretation of the results, and writing the manuscript. W Sun carried out the Invasion assay and three-dimensional culture of GBC-SD and SGC-996 cells in vitro. WZ Zhang and CY Ge carried out the nude mouse xenografts of GBC-SD and SGC-996 cells. W Sun and WZ Zhang were responsible for the existence of VM in GBC by using immunohistochemistry staining, TEM and micro-MRA technology in vitro and in vivo, respectively. All authors have read and approved the final manuscript.”
“Background Breast cancer is a heterogeneous disease of considerable social and economic burden.

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