(C) 2010 Wiley Periodicals, Inc. Environ Toxicol 26: 623-632, 2011.”
“Objective-To determine the
prevalence of cardiomyopathy and the relationship between cardiomyopathy and heart murmurs in apparently healthy cats.
Design-Cross-sectional study.
Animals-103 selleck chemicals llc privately owned, apparently healthy domestic cats.
Procedures-Cats were physically and echocardiographically examined by 2 investigators independently. Left ventricular wall thickness was determined via 2-dimensional echocardiography in short-axis and long-axis planes. Left ventricular hypertrophy was identified when end-diastolic measurements of the interventricular septum or posterior wall were >= 6 mm. Cats with left ventricular hypertrophy but without left ventricular dilatation were considered to have hypertrophic cardiomyopathy (HCM). The associations between heart murmurs and Doppler echocardiographic
velocity profiles indicative of dynamic ventricular outflow tract obstruction were evaluated.
Results-Heart murmurs were detected in 16 (15.5%; 95% confidence interval, 9.2% to 24.0%) cats; of these, 5 had cardiomyopathy. Cardiomyopathy was also identified in 16 (15.5%; 95% confidence interval, 9.2% to 24.0%) cats; 15 had HCM, and 1 had arrhythmogenic right ventricular cardiomyopathy. Of the cats with HCM, 11 check details had segmental left ventricular hypertrophy, 3 had diffuse left ventricular hypertrophy, and I
had borderline left ventricular hypertrophy with marked systolic anterior motion of the mitral valve. Sensitivity and specificity of auscultatory detection of a heart murmur for diagnosing cardiomyopathy were 31% and 87%, respectively. Echocardiographic evidence of late systolic acceleration within ventricular outflow tracts was associated with the existence of a heart murmur.
Conclusions and Clinical selleck compound Relevance-Cardiomyopathy was common in the healthy cats evaluated in this study. In apparently healthy cats, detection of a heart murmur is not a reliable indicator of cardiomyopathy. (J Am Vet Med Assoc 2009; 234: 1398-1403)”
“Objective: To evaluate otolaryngologic findings in obese prepubertal children with sleep-disordered breathing.
Methods: We prospectively evaluated 29 obese children referred by pediatric endocrinologist, complaining of snoring and without a history of nasal surgery or removal of the palatine tonsils and/or adenoids. Patients underwent ear, nose and throat (ENT) examination, endoscopy, measurements of weight, height, calculation of body mass index (BMI), assessment of BMI z-score and polysomnography, from which were divided into two groups: those with obstructive sleep apnea syndrome (nine children) and those with primary snoring (20 children). Then we proceeded to the statistical analysis of the data collected.