Similarly protease inhibitors are known to cause growth inhibition by interfering with digestion causing pancreatic hypertrophy and metabolic disturbance of sulfur amino acid utilization [8].During http://www.selleckchem.com/products/baricitinib-ly3009104.html the past several decades, the primary objective of plant breeding programs has been to increase yield, a quest that will remain a principal concern in providing the calorie intake required for the growing world population. However, equally important but largely overlooked in breeding programs is the nutritional quality of wheat whole meal particularly the protein quality and micronutrients concentrations and their bioavailability [5].The wheat quality characteristics are usually influenced by genotype, environmental factors, and interactions between genotype and environment.

Adverse environmental conditions such as extreme temperature and drought during the anthesis and grain filling period have been identified as major constraints to wheat protein content and composition [9, 10]. Most of the earlier studies were focused on the effect of either heat or drought stress during grain filling on composition of proteins and starch characteristics. Few studies have examined the combined effect of high temperature and drought on protein and gluten contents with limited emphasis on nutritional quality. However, little is known concerning the combined effect of sowing time and drought stress on nutritional quality of wheat whole meal. In our earlier work we analysed the effect of rain-fed and different sowing times on monomeric/polymeric proteins and starch pasting characteristics of wheat whole meal [11].

The study clearly indicated the significant variation in the content and composition of storage proteins under different sowing conditions. Rain-fed conditions resulted in generation of new correlations among various protein fractions and starch pasting characteristics, which were far from those observed under irrigated conditions. The study suggested that utilization of these new correlation trends observed between different protein components under rain-fed conditions could be useful for Drug_discovery enhancing protein content without affecting protein quality of wheat grains. However, the work was confined up to the level of monomeric and polymeric protein fractions and starch pasting characteristics. In the present study, therefore, we are attempting to further fractionate the protein to albumin-globulins and gliadin components and to observe the variation in the minerals and antinutrients, to better understand the effect of varying sowing conditions on wheat whole-meal quality.2. Materials and Methods2.1. Plant Material and Experimental ConditionsTwo wheat (T. aestivum L.