Management of these patients is controversial This review evalua

Management of these patients is controversial. This review evaluates the tumoral response, the surgical management and the potential results. Delta”
“We have revised a part of the diagnostic criteria for fulminant type 1 diabetes. The new criteria were set both to express the essence of this disease of rapid increase of patients’ blood glucose and to be highly sensitive to reduce the misdiagnosis. After analyzing the selleck data of 382 patients with newly-diagnosed fulminant type 1 diabetes, we adopted the glycated hemoglobin (HbA(1c)) level of 8.7% (National Glycohemoglobin Standardization Program [NGSP] value). The new criterion

indicates 100% of sensitivity and the best value by receiver operating characteristic curve analysis. In addition, we added a comment that ‘This value (HbA(1c) <8.7% in NGSP) is not applicable for patients with previously diagnosed glucose intolerance’ in the new criteria and also a comment that ‘Association with human leukocyte antigen DRB1*04:05-DQB1*04:01 is reported’ as a related finding. We did not revise the screening criteria and the other part of the diagnostic criteria, because they are still reliable. (J Diabetes Invest doi: 10.1111/jdi.12024,

2012)”
“Background: Recent resuscitation guidelines for infant cardiopulmonary resuscitation (CPR) emphasise that rescuers should minimise the interruption of chest compressions. To that end, supraglottic devices such as laryngeal mask airways (LMAs) are suggested Epigenetics inhibitor as a backup for airway management during infant CPR. We therefore compared the utility of the air-Q (R) LMA (air-Q) with that of the Soft Seal (R) LMA (Soft Seal) for infant CPR in an infant manikin.\n\nMethods: Twenty-four novice doctors in the anaesthesia department performed insertion and ventilation with air-Q and Soft Seal on an infant manikin with or without chest compression.\n\nResults: Two doctors failed to insert the Soft Seal without chest compression,

while nine failed during selleck screening library chest compression (P < 0.05). However, only one doctor failed to insert the air-Q without chest compression, and two doctors failed during chest compression. Insertion time was not significantly increased with chest compression using either device. Insertion time during chest compression was significantly shorter for the air-Q than for the Soft Seal (P < 0.05). The visual analogue scale (VAS) was used to evaluate difficulty of use (0 mm (extremely easy) to 100 mm (extremely difficult)). VAS scores did not change significantly by the addition of chest compression with either device; however, VAS scores during chest compression were significantly higher with Soft Seal than with the air-Q device.\n\nConclusion: We conclude that novice doctors find the air-Q easier to use than Soft Seal for emergency airway management during chest compression in infants, in an infant manikin. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

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