, 2009 and Zhang and Wang, 2004); 2) low-income individuals are less likely to consume nutritious foods (Lynch et al., 2004) and more likely to consume calorie-dense foods such as soda, sugar-sweetened beverages, and other processed foods (Cohen et al., 2010); and 3) fruit and vegetable Microtubule Associated inhibitor consumption, a proxy for healthy eating, is disproportionately lower among low-income subgroups (Drewnowski, 2009). In LA County, African

American and Hispanic women were more likely than white women to be overweight or obese. This observation, however, may be due to the higher representation of African Americans in the LA County sample. In contrast to recent U.S. Census estimates — African Americans accounted only for approximately 9% of the total county population (U.S. Census Bureau, 2012b), African Americans represented 42% of the LA case study

sample. In WV, racial differences were difficult to assess because more than 90% of health assessment participants were white. Although case studies provide important insights into regional differences in overweight and obesity — WV (rural) versus LA County (urban), inferences about the root causes of these regional disparities cannot be fully explained given the dissimilar methods used to collect the data. While it is possible that such factors as sparse open space, unsafe neighborhoods, an inefficient public transit system, limited access to grocery stores, and non-competitive food pricing (Community Preventive Services Task Force (CPSTF), 2011, French Ipatasertib in vitro et al., 2001, Larson et al., 2009, Moore et al., 2008 and National

Prevention Council (NPC), 2011) may all present important challenges to healthy eating and active living in both communities, the magnitude of how these factors differentially impact overweight and obesity prevalence across the two regions remain unclear and warrant further study. Unique regional preferences heptaminol for soda and customs in preparing food, for example, may have differential impact on overweight and obesity prevalence across the various subgroups in each jurisdiction. Barriers to healthy eating (e.g., access to fresh fruits and vegetables) that are thought to be similar may actually be dissimilar, as the solutions to the obesity epidemic in each community may be different. Whereas capital investments in grocery stores or places that sell fresh fruits and vegetables (e.g., farmers market) are likely important for mitigating shortages of food venues in WV, conversion of existing corner stores (abundant in the neighborhood) or safer and easier access to public transportation to go to farther-away locations may be more suitable for LA County. Further research is needed to examine these factors, as they are not the focus of these case study examples. The case study approach utilized in this article has several limitations.