001). Bovine isolates were found in bovine-associated CCs in 65.8% of the cases. Poultry and human isolates www.selleckchem.com/products/nvp-bsk805.html were found in the ST-21 CC in 15.1% and 36% of the cases, respectively. The ST-61 CC did not occur among poultry and human isolates. The ST-45 CC contained 69.7% of all the poultry isolates, 40.2% of the human isolates and 10.8%

of the bovine isolates. ST-61 (p < 0.001), ST-53 (p < 0.0001), ST-58 (p = 0.01), ST-451 (p = 0.02) and ST-883 (p = 0.001) were associated with the bovine host and contained 38.3% of the bovine isolates. None of the human or poultry isolates represented bovine-associated STs. ST-45 was associated with poultry (p < 0.0001) and human isolates (p FG-4592 order < 0.01) and was found in 66.7% of the poultry isolates, 32% of the human isolates and 4.2% of the bovine isolates. ST-50 was associated with human isolates (p < 0.0001) and was found in 34% of the human isolates, 15.1% of the poultry isolates and 3.3% of the bovine isolates. ST-137 was associated

with the human isolates (p < 0.01), but was absent from both other sources. Using BAPS, nearly all

estimation runs converged to the same solution with five www.selleckchem.com/products/Vorinostat-saha.html clusters having high PRKACG posterior certainty in its vicinity according to the program output. BAPS clusters 1 and 4 contained the majority of isolates (86.8%). BAPS cluster 1 contained all STs found in the ST-22, ST-45, ST-48, ST-283, and ST-658 CCs in addition to two significantly admixed STs in the ST-21 CC (Table 2). One ST of the ST-48 (ST-2955) and ST-658 CCs (ST-1967) was admixed as well. BAPS cluster 2 contained a total of three unassigned STs which were only found in human isolates. In BAPS cluster 3 the ST-677 CC was grouped together with two uncommon, unassigned STs. BAPS cluster 4 comprised all, but two, STs of the ST-21 CC, all STs from the ST-52, ST-206, ST-257 and ST-1287 CCs and one ST (ST-618) from the ST-61 CC, which was significantly admixed. The remainder of the ST-61 CC formed a distinct cluster (cluster 5), with no admixed STs and contained only bovine isolates. Table 2 Distribution of clonal complexes and sequence types accordingly BAPS clusters.