Methods: Twenty

refractory FD patients with high levels of emotional distress who have failed to all motility-type agents or other gastrointestinal treatments were as FD group. Twenty healthy people were chosen as control. Personality traits and VT were observed for every people. Eysenck Personality MLN2238 Questionnaire (EPQ) was used to assess the personality of neuroticism (N), psychoticism (P), extroversion (E), phlegmatic temperament, sanguine temperament, choleric temperament and melancholic temperament. HF and RMSSD as the indices of HRV were measured by 24 h Holter, which were used to as the indicator of vagal tone (VT). The low VT was low HF and RMSSD declining. Results: (1) The value of HF and RMSSD were significantly lower in FD group than healthy group (P < 0.05); (2) The scores of P and N in FD group were higher check details than those of healthy group (P < 0.05);

But the scores of E in FD group was lower (P < 0.05); (3) The declining HF was related to neuroticism (N) in two groups (P < 0.05), which was no relationship with psychoticism (P) and extroversion (E) (P > 0.05); Interestingly, the patients with melancholic temperament have lower HF than other traits in healthy group (p < 0.05). Conclusion: The study found that the refractory FD patients have personality tendency of neuroticism, introversion, psychoticism, and low VT. In the healthy group, the personality of melancholic temperament (low scores of E and high scores of N) also has appeared low HF, and low HF was related to high N. These results show melancholic 上海皓元 temperament has tendency of vagus nerve dysfunction, and this trait may be more easily to suffer from refractory FD. Therefore, refractory FD may be based on personality traits, especially melancholic temperament. Key Word(s): 1.

Refractory FD; 2. Personality Traits; 3. Vagal Tone; Presenting Author: XINGYU LIU Additional Authors: HAO LIANG Corresponding Author: XINGYU LIU Affiliations: Chinese PLA General Hospital; Chinese PLA General Hospital Objective: To analyze the clinical and endoscopic characteristics, and treatment methods of 11 adult Henoch-Schonlein Purpura (HSP) with gastrointestinal involvement so as to improve the early diagnosis and treatment of this disorder. Methods: A retrospective study in 11 adult HSP patients with gastrointestinal involvement enrolled from 2008 to 2012 at Chinese PLA General Hospital was conducted. Results: The 11 adult HSP patients with gastrointestinal involvement enrolled in this study were mainly youth, and 5 patients (45.4%) have obvious inducing causes. All the patients had cutaneous purpura and abdominal pain, and the severity of abdominal pain was not concordant with physical signs. Abdominal pain occurred prior to cutaneous purpura in 7 patients (63.6%), and 8 patients (72.7%) had gastrointestinal bleeding.